HPE P50312-B21 64GB DDR5 SDRAM Memory Module

The HPE P50312-B21 64GB DDR5 SDRAM Memory Module is engineered to power modern, CPU-core-dense systems with unprecedented memory bandwidth and efficiency. As data centers push toward higher core counts and more complex workloads, DDR5 memory delivers the bandwidth per core needed to keep processors fed, minimize latency bottlenecks, and maximize overall system performance. This high-density module is a purpose-built solution for HPE servers and other enterprise-class configurations that demand reliable, scalable, and future-proof memory. By adopting DDR5 technology, this module helps workloads such as virtualization, in-memory databases, real-time analytics, AI inference, and large-scale transactional processing run smoother, faster, and cooler than previous generations.

Designed to integrate seamlessly into supported server platforms, the P50312-B21 combines robust data integrity, improved power efficiency, and higher memory densities into a single DIMM. For administrators and IT teams, this means fewer memory bottlenecks, longer periods between upgrades, and more headroom for expanding memory pools as workloads evolve. In practice, you’ll experience quicker boot times, faster cache access for frequently used datasets, and enhanced multi-threaded performance as multiple cores access large memory arrays concurrently. The result is a more responsive infrastructure that can handle peak-demand scenarios with confidence, while preserving energy efficiency and thermal performance in dense rack deployments.

Beyond raw speed, the HPE P50312-B21 is built with enterprise-grade reliability in mind. Server environments demand consistent availability, rigorous error checking, and predictable behavior under load. DDR5 brings improved memory signaling and stricter timing controls to maintain data integrity at higher speeds. For organizations investing in long-term IT strategies, this module is a strategic upgrade that aligns with modern memory architectures, enabling more consistent service levels, better virtualization density, and improved capacity planning. In short, upgrading to 64GB of DDR5 memory per module makes it feasible to consolidate workloads, support larger datasets in memory, and prepare for future software stacks that require more memory bandwidth and capacity.

From a total-cost-of-ownership perspective, the P50312-B21 delivers value through higher performance per watt and fewer memory-related bottlenecks. As CPUs scale up core counts, the need for memory bandwidth grows in tandem. DDR5 memory is designed to scale with these advancements, offering better channel utilization, higher data-rate capabilities, and improved reliability features that are essential for data-center-grade operations. Whether you’re consolidating virtual machines, running memory-hungry databases, or accelerating batch processing, this module provides a solid foundation for sustained performance. In environments where uptime is critical, choosing a memory module that is specifically designed for HPE servers helps ensure compatibility, optimized firmware integration, and tested reliability across supported configurations. The result is a more predictable performance curve and a smoother path to future upgrades as technologies continue to advance.

• 64 GB capacity per DIMM — Ideal for memory-intensive workloads, large-scale virtualization, in-memory databases, and AI/ML inference pipelines that demand substantial resident data.
• DDR5 technology for higher bandwidth — DDR5 delivers improved bandwidth, faster data rates, and enhanced efficiency to keep up with modern CPUs and multi-core workloads.
• Server-grade reliability and compatibility — Designed for HPE servers and other enterprise-class systems, ensuring reliable operation in data centers and mission-critical environments.
• Easy integration and scalability — A straightforward upgrade that fits standard DIMM slots, enabling scalable memory expansion as workloads grow.
• Optimized power efficiency and thermal performance — DDR5 memory reduces power per bit and supports better thermal characteristics in dense rack deployments.

Technical Details of HPE P50312-B21 64GB DDR5 SDRAM Memory Module

• Capacity: 64 GB per DIMM
• Memory Type: DDR5 SDRAM
• Form Factor: DIMM
• Module Speed: DDR5 (speed specifications vary by system and may require compatible CPUs and motherboard/servers)
• Intended Use: Server-class memory designed for HPE servers and other enterprise-class x86 systems requiring high bandwidth and reliability

how to install HPE P50312-B21 64GB DDR5 SDRAM Memory Module

• Prepare the system — Power down the server completely, unplug all power sources, and ground yourself to prevent static discharge. Remove exterior panels to access the memory slots according to your server’s maintenance manual.
• Identify the correct memory slots — Locate the available DIMM slot(s) defined by your server’s memory topology. In multi-channel configurations, follow the manufacturer’s guidance for populated slots to maximize bandwidth and interleaving.
• Handle with care — Grasp the DIMM by the edges, avoiding contact with gold connectors or any components. Do not stack or force modules into slots; ensure alignment with the notch.
• Install the module — Align the notch on the module with the slot key and apply even pressure along both ends of the DIMM until the locking latches click into place, securing the module firmly.
• Verify and power up — Replace the access panel, reconnect power, and boot the server. Enter the BIOS/UEFI or the operating system utility to verify that the memory is detected and running at the expected speed and configuration. Run a memory diagnostic if available to confirm stability.

Frequently asked questions

• Q: What is the capacity of this memory module? A: This module has a capacity of 64 GB per DIMM, providing substantial headroom for virtualization, databases, and memory-intensive workloads.
• Q: What type of memory is the HPE P50312-B21? A: It is a DDR5 SDRAM memory module designed for server-class use, delivering higher bandwidth and improved efficiency compared to previous generations.
• Q: Is this memory compatible with all servers? A: The P50312-B21 is designed for HPE servers and other enterprise-class x86 systems. Always verify compatibility with your specific server model and firmware version before upgrading.
• Q: What benefits does upgrading to DDR5 bring? A: DDR5 offers higher data rates and bandwidth, improved power efficiency, higher memory densities, and better scalability to support modern CPUs and demanding workloads such as virtualization and AI inference.
• Q: How should I install this memory module? A: Follow standard static-safe installation procedures: power down the system, discharge static electricity, identify an appropriate DIMM slot, insert the module with even pressure until it clicks, reseal panels, and verify in BIOS/UEFI that memory is detected and operating correctly.
• Q: What about warranty and support? A: Warranty terms vary by vendor and region. Check with your seller or HP for the specific warranty coverage on the P50312-B21 memory module and any device-level compatibility or firmware requirements.