HPE P5620 6.40 TB NVMe MU SSD – 2.5" U.2 PCIe 4.0 Enterprise Storage

Meet the HPE P5620 6.40 TB Solid State Drive, a high-performance, mixed-use NVMe SSD engineered to power data-centric workloads in today’s demanding data centers. With a 2.5" U.2 form factor and a PCIe 4.0 interface, this drive delivers rapid data access, low latency, and sustained throughput across diverse enterprise environments. It is purpose-built for a broad spectrum of workloads—from Big Data analytics and cloud computing to high-performance computing, business intelligence, database applications, and virtualization—helping organizations drive faster insights, accelerate decision-making, and improve overall data efficiency. The P5620 MU SSD integrates enterprise-grade reliability and endurance features to support continuous operation in dense server configurations, ensuring you can scale your storage architecture without compromising performance or data integrity.

Designed for mixed-use scenarios, the HPE P5620 blends the performance of NVMe with the resilience demanded by production workloads. It leverages PCIe Gen4 speed to shorten I/O paths and reduce bottlenecks, enabling databases to process transactions faster, analytics pipelines to ingest data more quickly, and virtualized environments to spin up workloads with minimal latency. In data centers where space is at a premium, this 2.5" drive provides a compact, scalable solution that fits into standard enterprise backplanes and back-to-back drive cages. Beyond raw speed, the P5620 MU SSD emphasizes data protection and operational efficiency, featuring robust error correction, wear leveling, and efficient power management designed to sustain workloads over long duty cycles.

For IT teams seeking to optimize total cost of ownership, the P5620 delivers predictable performance and simplified lifecycle management. Its enterprise-grade design supports hot-swapping in compatible server platforms and is engineered to maintain consistent performance under sustained load. Organizations can deploy the P5620 across a variety of roles—whether as a primary storage tier for hot data, a rapid cache acceleration layer in hybrid configurations, or as cold data archiving in scalable storage pools—while enjoying reduced latency, improved IO consistency, and strong endurance characteristics that help extend drive life in mixed-use deployments.

As part of a broader HPE storage ecosystem, the P5620 MU SSD integrates with enterprise software stacks and management tools to streamline firmware updates, monitoring, and health checks. Administrators benefit from proactive telemetry and robust reliability features that minimize unplanned downtime and support proactive maintenance. The drive’s architectural design also supports data integrity through built-in protection mechanisms, helping to safeguard critical information across workloads that demand both speed and dependability. In short, the HPE P5620 6.40 TB NVMe MU SSD is engineered to enable faster data access, higher utilization of compute resources, and more efficient, scalable storage for modern enterprises.

• High-performance mixed-use architecture: engineered to handle a wide range of workloads—from analytics to virtualization—with consistent latency and sustained throughput across diverse applications and user demands.
• Massive capacity in a compact form: 6.40 TB of solid-state storage in a 2.5" U.2 drive, enabling dense, scalable configurations in modern server and storage backplanes without sacrificing performance.
• NVMe over PCIe 4.0 for rapid data access: leverages PCIe Gen4 x4 and NVMe interfaces to dramatically reduce I/O overhead, accelerating data-driven workflows and real-time analytics.
• Enterprise reliability and endurance: designed with robust data protection features and durable endurance suitable for mixed-use workloads that require steady operation and long life in production environments.
• Efficient power and thermal design: optimized for data-center efficiency, delivering strong performance while managing power consumption and thermal output in dense deployments.

Technical Details of HPE P5620 6.40 TB Solid State Drive

• Capacity: 6.40 TB
• Form factor: 2.5" (SFF) U.2
• Interface: PCIe Express 4.0 x4
• Protocol: NVMe (non-volatile memory express)
• Drive type: Mixed Use (MU) solid-state drive
• Target workloads: Big Data analytics, cloud computing, high-performance compute, database applications, virtualized environments
• Warranty: Enterprise-grade warranty

How to install HPE P5620 6.40 TB Solid State Drive

Installing the HPE P5620 MU SSD is straightforward in servers and storage systems that support a 2.5" U.2 drive bay and NVMe over PCIe backplanes. Begin by preparing your server or chassis for an NVMe drive, ensuring you have a compatible backplane or hot-swap tray that accepts U.2 drives. Power down the system and unplug the power cords to prevent any electrical risk. If you are replacing an existing drive, remove the old unit from its bay following the platform’s service manual. If you are adding the drive to an empty slot, simply open the drive bay to reveal the backplane and connect the U.2 data and power interface cables to the drive or backplane.

Insert the HPE P5620 MU SSD into the drive bay or backplane with the label facing outward for easy identification. Secure the drive with the mounting screws to prevent movement during operation. Reconnect any cables you detached and reseat the server components as required. Power on the system and enter the BIOS/UEFI configuration to confirm that the NVMe device is detected. Some systems may require you to enable NVMe support or configure the PCIe slot to operate in the correct mode. Save the changes and boot into your operating system.

Once the OS is active, initialize the new drive using your preferred disk management tool (for example, Disk Management in Windows, or diskutil/parted in Linux). Create one or more partitions, assign file systems appropriate to your workloads (ex: NTFS, exFAT, or Linux file systems like ext4 or XFS), and format the drive. It is advisable to align partitions properly to optimize performance with NVMe devices. After formatting, you can begin moving or indexing data onto the new drive, or integrate it into your storage pool as a tier or cache, depending on your data-center strategy. Finally, ensure your firmware is up to date using the vendor’s management utilities to maintain compatibility and reliability across your fleet of P5620 drives.

For ongoing maintenance, monitor the drive’s health and firmware status through your server or storage management software. Regular firmware updates can improve performance, security, and endurance, while monitoring tools can alert you to potential issues before they impact production workloads. By following these steps, you can maximize the benefits of the HPE P5620 MU SSD and ensure a smooth, scalable deployment within enterprise environments.

Frequently asked questions

Q: What does MU stand for in HPE P5620 MU SSD?
A: MU stands for Mixed Use. It is designed to support a range of workloads that mix read and write operations across diverse enterprise applications, providing balanced performance and endurance suitable for both data-intensive and latency-sensitive tasks.

Q: Is the HPE P5620 compatible with NVMe-enabled servers and backplanes?
A: Yes. The drive is built for NVMe over PCIe 4.0 and requires a 2.5" U.2 drive bay and a compatible backplane or PCIe NVMe interface in your server. Ensure your system firmware and drivers are up to date to maximize compatibility and performance.

Q: What workloads is the P5620 MU SSD best suited for?
A: It is well-suited for Big Data analytics, cloud infrastructure, virtualized environments, database applications, business intelligence, and high-performance compute tasks. Its mixed-use design delivers strong throughput and low latency across these workloads, helping accelerate data processing and analytics pipelines.

Q: How should I manage firmware updates for the P5620?
A: Use your server or storage management tools to monitor drive health and apply firmware updates when available. Keeping firmware current helps maintain reliability, performance, and compatibility with other components in your storage stack.

Q: What are best practices for deploying the P5620 in a dense data-center environment?
A: Plan for adequate cooling in dense racks, ensure proper backplane compatibility, and consider using the P5620 as part of a tiered storage strategy. Use enterprise-grade power management, monitor thermal margins, and schedule regular health checks to sustain performance and drive longevity in mixed-use deployments.

Note: For exact warranty terms, firmware versions, and field-verified compatibility with specific server models, consult the HPE product documentation or your authorized HPE distributor.